Fig. 1. a. Body weight (g); b. Heart rate (BPM); c. Heart Weight (g); d. Heart weight/ tibia length ratio (g/cm) at end of treatment 28 days after surgery here were 6 animals in each group. * p<0.001 vs. Cont. † p<0.001 vs. TIC. ASA- aspirin; Cont- control; PRAS- prasugrel; TIC- ticagrelor.